The village of Poibrene is located in South-Central Bulgaria. and is included in Municipality Panagyurishte (Pazardjik District). It is located at 18 km west of the municipal center town of Panagyurishte. The large dam Topolnitsa is only at 1 km to the west of the village. Due to the dam, the baths and the clear natural environment many citizens of Panagyurishte have summer houses in or near the Poibrene. Several monuments there commemorate participants in the April Uprising.